Background: Novel coronavirus (COVID-19) has been associated with a hypercoagulable state which has led to the following complications: increased risk for deep vein thrombosis, pulmonary embolism, acute coronary syndrome, and acute stroke.
Case presentation: We present the case of a 66-year-old, Hispanic male who was admitted to the intensive care unit for severe respiratory illness secondary to the COVID-19 infection. The patient suffered an acute stroke on day 7 at the hospital.
Conclusion: Emerging evidence suggests a coagulation dysfunction with the COVID-19 infection particularly in patients with severe illness with or without comorbid conditions. Amidst the current global pandemic, acute stroke in the setting of respiratory failure, should prompt suspicion for coronavirus infection.